Synergy Bioscience is at the forefront of pharmacodynamics (PD) studies, playing a pivotal role in the early stages of drug development. Our cutting-edge PD assessments yield critical insights into the biological effects of new therapeutic agents, informing the design of subsequent clinical trials and aiding in the optimization of treatments.

Integrating PD Biomarkers for Enhanced Drug Development

Our application of PD biomarkers in both preclinical and clinical studies is integral to establishing effective dosing regimens and therapeutic efficacy. This information is not just data; it’s the roadmap guiding safer and more effective patient care.

Prioritizing Safety and Efficacy

At Synergy Bioscience, we understand that the heart of drug development lies in the balance of safety and efficacy. Our methodologies for monitoring PD effects are meticulously crafted to align with the specific endpoints of your study—ensuring they are not only appropriate but also reliable and reproducible across various conditions.

Informed Decision-Making with Early Go/No-Go Assessments

Our PD biomarker assessments are designed to empower you with the data needed to make informed, early go/no-go decisions. This approach enables the selection of the most promising drug candidates and the rational combination of targeted agents, optimizing the potential for successful outcomes.

Expertise in Assay Development and Validation

Leverage the expertise of our scientific team, which boasts a broad spectrum of specialized knowledge in a variety of assays:

 Soluble Biomarkers: We offer precise measurement of soluble biomarkers, providing insights into the systemic effects of drugs.
 Cellular Phenotyping: Our assays for cellular phenotyping reveal the impact of compounds on cellular behavior and characteristics.
 Molecular Events: We map the molecular events that drugs induce, ensuring a comprehensive understanding of their mechanisms of action.

Commitment to Quality and Regulatory Excellence

Our commitment at Synergy Bioscience extends beyond assay development:

 Industry Leadership: We are recognized as industry-leading biomarker experts, utilizing innovative platforms that reflect our science-driven dedication to quality.
 Regulatory Insight: Our team is well-versed in the regulatory expectations surrounding biomarker analytical validations, ensuring compliance with the context of use.
 Proven Track Record: We have a history of successfully developing, optimizing, and validating a wide array of biomarker assays under stringent regulatory conditions, including Good Clinical Laboratory Practice (GCLP), Clinical Laboratory Improvement Amendments (CLIA), and for non-regulated applications.

Partnering with Synergy Bioscience

Choosing Synergy Bioscience means partnering with a team that offers unparalleled expertise in PD assessment. Our industry-leading techniques and robust validation processes are complemented by a thorough understanding of regulatory landscapes, ensuring that your drug development journey is supported by a foundation of excellence.

Together, we can accelerate the drug development process, ensuring that every step from the laboratory to the clinic is taken with confidence. Trust in Synergy Bioscience to be your guide in the intricate journey of drug development, where every discovery is a step towards improving patient outcomes.

To discuss how Synergy Bioscience can help you, please contact us