Analytical Chemistry

Synergy Bioscience is committed to providing expert and timely analytical chemistry services with a level of quality and reliability you can trust. We offer a wide range of analytical services, including compendial testing according to USP/NF, EP, BP, JP, ACS, AOAC, ISO/IEC 17025, ISO 10993, and customer-specified monographs, to support raw materials, in-process analysis, and finished product release testing that will meet all of your product needs.

Our team of experts specializes in testing a variety of drug products, drug substances, and dosage forms, including tablets, capsules, semi-solids, parenteral, sterile, transdermal, and inhalation products. We have built a solid reputation in the industry for our high-quality services and timeliness since 2016.

At Synergy, our mission is to provide you with the analytical solutions you need to achieve your drug development goals quickly and easily.

Our testing services include, but are not limited to:

• Full amino acid and therapeutic protein sequencing and profiling
• PCR and DNA sequencing to support drug product R&D activities
• Chromatographic testing using HPLC
• Pharmaceutical product characterization using Mass Spectrometry
  HPLC-MS/MS or UPLC-MS/MS
• Residual solvents identification and quantitation using GC-MS
  (Agilent MSD with El and Cl ionization source)
• Trace metals by ICP-MS / ICP-OES
• Cleaning validation samples testing using TOC
  (Total Organic Carbon analyzer)
• Extractables/Leachables studies using LC-MS, GC-MS, IC-MS
• Organic volatile impurities testing using GC
  (direct injection and headspace capability (detectors: FID, TCD, and NPD))
• UV-Vis spectrophotometer
• Dissolution testing
• Moisture determination
  (Karl Fischer, direct titration and coulometric titration)
• Capillary Electrophoresis testing CE
• Fluorescent spectrophotometer
• Thermal analysis (TGA and DSC)
• Container/Closure testing
• Particle size distribution (laser diffraction)
• Melting point determination
• Residual solvents identification and quantitation
• Viscosity determination (Brookfield and capillary tube viscometer)

• Acrylamide using LC-MS/MS
• Aflatoxins M1 using LC-MS/MS
• Benzo(a)pyrene using HPLC-FLD
• Dioxins and PCBs using HRGC/HRMS
• Ethanol Residues using SHS-GC/MS
• Free 3-MCPD using GC-MS/MS
• Multi-Mycotoxins using LC-MS/MS
• Nitrate and Nitrite Ions using Ion Chromatography
• Overall Migration from Materials and Articles (plastics) in contact with
  Foodstuffs into Aqueous Food Simulants by Total Immersion
• Patulin using LC-MS/MS.
• Sudan Dyes using LC-MS/MS
• Synthetic Sweeteners using LC-MS/MS
• Total fat (%) using Soxhlet Extraction
• Veterinary Drugs using LC-MS/MS
• Vitamin B Complex using LC-MS/MS
• Pesticide Residues in Foods using LC-MS/MS & GC-MS/MS
• Nitrogen analysis
• Oxygen and Carbon Dioxide gas analysis
• Chemical identification and quantification test
• Impurities profile
• Particulate matter
• Compendial testing methods verification