At Synergy Bioscience, we are dedicated to advancing the field of drug development with our comprehensive suite of Drug Metabolism and Pharmacokinetics (DMPK) services. Our industry-standard assays, tailored drug metabolism research, and Investigational New Drug (IND)-enabling studies are designed to streamline the path from discovery to clinical trials.
Comprehensive DMPK Assays and Research
Our expertise in DMPK assays extends to a thorough assessment of drug-drug interaction potential, metabolic stability, metabolite profiling, and protein binding. These assessments are crucial in understanding the pharmacokinetics of new drug candidates and in predicting their behavior in biological systems.
Tailored Solutions for Drug Development Phases
Whether you are at the threshold of discovery, navigating the intricacies of lead optimization, or in the crucial phase of candidate selection, Synergy Bioscience stands ready to assist. We believe in a collaborative approach, working closely with our clients to define the research strategy that aligns with the specific requirements of each stage of development.
Metabolic Stability and Customization
We specialize in metabolic stability DMPK assays, which are instrumental in determining the potential half-life of compounds in vivo. Our analytical techniques are capable of examining test articles across various enzyme sources, including:
• Membrane preparations from both recombinant bacteria and eukaryotic cells for targeted studies
Customized Time Points and Deliverables
Each project at Synergy Bioscience is treated with the utmost individuality. Time points for analysis are customized to meet the unique timeline of your study, ensuring that data is captured at the most relevant intervals. Our deliverables are comprehensive, encompassing raw data, percentage of compound remaining, and calculated half-life values. These can be formatted into formal reports that are submission-ready for regulatory bodies or presented as raw data tables in Excel format, depending on your requirements.
Regulatory Submission and Reporting
The journey from lab bench to bedside is paved with regulatory milestones. Our formal reports are crafted to meet the stringent demands of regulatory agencies, ensuring that your submission is backed by robust and reliable data. For those requiring a more flexible approach, we offer informal reporting that can be quickly integrated into ongoing research processes.
Our Commitment to Innovation and Excellence
At Synergy Bioscience, we are more than just a service provider; we are your partners in innovation. Our commitment to excellence is reflected in our state-of-the-art laboratory facilities, our skilled team of scientists, and our adherence to the highest quality standards.
Partner with us at Synergy Bioscience, where your drug development aspirations are transformed into tangible outcomes through strategic research, meticulous analysis, and comprehensive reporting. Let’s navigate the complex landscape of drug discovery and development together, forging a path toward therapeutic breakthroughs and improved patient outcomes.